Blazso G, Gabor M, Schonlau F, Rohdewald P. Pycnogenol accelerates wound healing and reduces scar formation. Urologia. Pycnogenol is the registered trademark name for a French formula. (Sofiia) 2007;46(5):7-12. J Am Acad Child Adolesc Psychiatry 1999;38:357-8. Eur Bull Drug Res 1999;7:14-18. Cho, K. J., Yun, C. H., Packer, L., and Chung, A. S. Inhibition mechanisms of bioflavonoids extracted from the bark of Pinus maritima on the expression of proinflammatory cytokines. Phytother Res 2002:16:S1-S5. Growth Horm.IGF.Res. View abstract. Angiology 2005;56(6):699-705. Chayasirisobhon, S. Use of a pine bark extract and antioxidant vitamin combination product as therapy for migraine in patients refractory to pharmacologic medication. Peng, Q. L., Buz'Zard, A. R., and Lau, B. H. Pycnogenol protects neurons from amyloid-beta peptide-induced apoptosis. Reuter, J., Wolfle, U., Korting, H. C., and Schempp, C. Which plant for which skin disease? Alternative Therapies 2001;7:S17. View abstract. FEBS Letters 2000:465;93-7. View abstract. J Ocul.Pharmacol Ther 2005;21(1):28-35. Drieling, R. L., Gardner, C. D., Ma, J., Ahn, D. K., and Stafford, R. S. No beneficial effects of pine bark extract on cardiovascular disease risk factors. Pycnogenol ® is a patented water-soluble pine bark extract containing 65-75% proanthocyanidins. Gen Physiol Biophys. View abstract. 2007;10(3-4):151-157. When talking about using antioxidants for cancer, here are a few things you should know. View abstract. Cancer Scams Chemotherapy Dementia Dentistry Diabetes Doctor Oz Flu Shot Immunization Influenza Medical Kidnapping Men's Health Oncology Outbreak Prevent Cancer Psychiatry Side Effects SSRI Statins Superbugs Thimerosal Vaccine … A., Maritim, A. C., Sanders, R. A., and Watkins, J. Postepy Hig.Med Dosw.(Online.) Research done by Michael Lisanti MD at the Kimmel Cancer Center in Philadelphia, Pennsylvania found that cancer cells produce and release a lot of hydrogen peroxide, which damage nearby healthy cells in the tissues called fibroblasts. Relationship between changes in plasma amino acids and depression in alcoholic patients. Suzuki, N., Uebaba, K., Kohama, T., Moniwa, N., Kanayama, N., and Koike, K. French maritime pine bark extract significantly lowers the requirement for analgesic medication in dysmenorrhea: a multicenter, randomized, double-blind, placebo-controlled study. 2011;115(4):461-465. View abstract. View abstract. J Med Food 2001;4(4):201-209. Fitzpatrick DF, Bing, Rohdewald P. Endothelium-dependent vascular effects of Pycnogenol. Makes sense, as much more vitamin C would be produced. 2006;60:316-321. 2010;24(3):438-444. And they don't use enough. 2010;77(1):43-51. View abstract. Diabetes medications are also used to lower blood sugar. Roseff SJ, Gulati R. Improvement of sperm quality by pycnogenol. View abstract. View abstract. View abstract. Ronuv focuses on oxygen creation in cancer cells and help OxyDHQ produce oxygen in cancer cells too. B., Lau, B. H., Ide, N., and Rong, Y. Pycnogenol inhibits macrophage oxidative burst, lipoprotein oxidation, and hydroxyl radical-induced DNA damage. View abstract. Liu FJ, Zhang YX, Lau BH. At the same time they work to prevent free radical damage to healthy cells. View abstract. View abstract. Grosse Duweler K, Rohdewald P. Urinary metabolites of French maritime pine bark extract in humans. The effect of Pycnogenol on the erythrocyte membrane fluidity. J Atten Disord 2002;6:49-60.. View abstract. J Invest Dermatol. Dvorakova, M., Sivonova, M., Trebaticka, J., Skodacek, I., Waczulikova, I., Muchova, J., and Durackova, Z. Free Radic.Res 2000;32(2):115-124. Dvorakova, M., Jezova, D., Blazicek, P., Trebaticka, J., Skodacek, I., Suba, J., Iveta, W., Rohdewald, P., and Durackova, Z. Urinary catecholamines in children with attention deficit hyperactivity disorder (ADHD): modulation by a polyphenolic extract from pine bark (pycnogenol). 2007;24(1):7-14. Grimm, T., Schafer, A., and Hogger, P. Antioxidant activity and inhibition of matrix metalloproteinases by metabolites of maritime pine bark extract (pycnogenol). There is no reference nutrient intake (RNI) for red clover but in a three-year trial, scientists gave high-dose treatments of up to 120mg a day with no ill-effects. Reduction of cardiovascular disease risk factors by French maritime pine bark extract. View abstract. Gulonolactone oxidase is used by the liver to make vitamin C from glucose. View abstract. home >  vitamins, herbs, dietary supplements a-z listpycnogenol. 2003;23:1189-1198. However cancer cells keep producing hydrogen peroxide and don't turn off. Hasegawa, N. Stimulation of lipolysis by pycnogenol. Inhibition of smoking-induced platelet aggregation by aspirin and pycnogenol. Phytother.Res. Cheshier JE, Ardestani-Kaboudanian S, Liang B, et al. Clin Appl.Thromb.Hemost. View abstract. View abstract. In our energetic testing, vitamin C IVs test very good in healing power for dealing with cancer. PrugX was developed to take advantage of this hydrogen peroxide production and release that Dr. Lisanti observed. Eur J Clin Nutr 1989;43 Suppl 2:43-8. Virgili F, Pagana G, Bourne L, et al. Life Sci 1996;58:87-96. Your brain would have less inflammation, be cleaner and function better, reducing the likelihood of developing dementia, Alzheimer's and Parkinson's disease. Phytother.Res 2009;23(3):297-302. Effect of tocotrienols on the growth of a human breast cancer cell line in culture. When used in therapeutic doses, Vitamin E energetically tests at 230 for its value as an antioxidant for cancer fighting. Diabetes: In theory, high doses of pycnogenol might decrease blood sugar too much in people with diabetes. Visit the FDA MedWatch website or call 1-800-FDA-1088. View abstract. Kohama T, Negami M. Effect of Low-dose French Maritime Pine Bark Extract on Climacteric Syndrome in 170 Perimenopausal Women: A Randomized, Double-blind, Placebo-controlled Trial. Nutr.Res. Kim, Y. G. and Park, H. Y. Again unfortunately, energetic testing puts Proto... or Can... at a good but not great level of 330. Liu, X., Wei, J., Tan, F., Zhou, S., Wurthwein, G., and Rohdewald, P. Pycnogenol, French maritime pine bark extract, improves endothelial function of hypertensive patients. Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. But what happens if you are giving someone with cancer very high doses of vitamin C, through IVs? View abstract. Phytother Res 2005;19(7):647-648. Anticancer Res 2000;20(4):2417-2420. Macrides, T. A., Shihata, A., Kalafatis, N., and Wright, P. F. A comparison of the hydroxyl radical scavenging properties of the shark bile steroid 5 beta-scymnol and plant pycnogenols. Use 1 to 3bottles per month. Up to two thirds of our exposure to chlorine is due to inhalation of steam and skin absorption while showering. Huynh, H. T. and Teel, R. W. Effects of intragastrically administered Pycnogenol on NNK metabolism in F344 rats. Araghi-Niknam, M., Hosseini, S., Larson, D., Rohdewald, P., and Watson, R. R. Pine bark extract reduces platelet aggregation. Fitoterapia 2000;71:236-44. J Psychopharmacol. Prim.Care Respir.J 2010;19(4):307-314. View abstract. View abstract. Huynh, H. T. and Teel, R. W. Effects of pycnogenol on the microsomal metabolism of the tobacco-specific nitrosamine NNK as a function of age. View abstract. FEBS Letters 1998;431:315-8. Phytother.Res. Res Commun.Mol Pathol.Pharmacol 1996;91(1):65-75. Schoonees, A., Visser, J., Musekiwa, A., and Volmink, J. Pycnogenol(R) (extract of French maritime pine bark) for the treatment of chronic disorders. Some herbal products, such as pycnogenol, fennel or combination products, might provide some relief from menstrual cramps. Eating optimal amounts of apricot pits comes in at 127. Free Radic.Res 2006;40(7):673-683. Insufficient Evidence to Rate Effectiveness for... vitamins, herbs, dietary supplements a-z list. Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others. Integr.Med. Sickle cell anemia: a potential nutritional approach for a molecular disease. J Inflamm. Acupressure. 2005;31(7 Pt 2):873-880. 2009;9(4):461-476. Ohkita, M., Kiso, Y., and Matsumura, Y. Pharmacology in health foods: improvement of vascular endothelial function by French maritime pine bark extract (Flavangenol). J Sex Marital Ther 2003;29:207-13.. View abstract. View abstract. Eur Bull Drug Res 1999;7:19-25. Sharma, S. C., Sharma, S., and Gulati, O. P. Pycnogenol prevents haemolytic injury in G6PD deficient human erythrocytes. Another way to look at it is that cancer cells are seeds that need the correct micro-environment in which to grow. It is also used for preventing disorders of the heart and blood vessels, including stroke, heart disease, and varicose veins. Combined with high acidity and low oxygenation, you've got a prescription for cancer. Redox.Rep. Phytother.Res. View abstract. Am J Psychiatry 1984;141:1212-5. Rohdewald P. Reducing the risk for stroke and heart infarction with pycnogenol. J Reproductive Med 2013;58(1):39-47. (detailed description of each of the ratings). 2006;12(2):205-212. 2008;22(4):518-523. Bito T, Roy S, Sen CK, Packer L. Pine bark extract pycnogenol downregulates IFN-gamma-induced adhesion of T cells to human keratinocytes by inhibiting inducible ICAM-1 expression. Pycnogenol® can help control blood pressure, which helps improve overall heart health. B., III. Panminerva Med. Toxicol Appl.Pharmacol 10-1-2000;168(1):64-71. It is not just drinking chlorinated water that is the problem. Baumann, L. How to prevent photoaging? View abstract. Cells are known to produce hydrogen peroxide, for example, to signal the immune system to heal wounds. Prevention of post thrombotic syndrome with Pycnogenol(R) in a twelve month study. View abstract. The mechanism of action is unclear. Belcaro, G., Cesarone, M. R., Errichi, B., Di, Renzo A., Grossi, M. G., Ricci, A., Dugall, M., Cornelli, U., Cacchio, M., and Rohdewald, P. Pycnogenol treatment of acute hemorrhoidal episodes. Phytother Res 2010;24:1115-9. Energetic testing comes in at 43 for high dose Vitamin C as an antioxidant for cancer. Angiology 2006;57(5):569-576. Pavone, C., Abbadessa, D., Tarantino, M. L., Oxenius, I., Lagana, A., Lupo, A., and Rinella, M. [Associating Serenoa repens, Urtica dioica and Pinus pinaster. Pharmazie 2000;55:364-8. Hypertension 2010;55(6):1310-1311. 2-15-2000;374(2):347-355. 2008;13(6):271-276. View abstract. van Jaarsveld, H., Kuyl, J. M., Schulenburg, D. H., and Wiid, N. M. Effect of flavonoids on the outcome of myocardial mitochondrial ischemia/reperfusion injury. Acta Obstet Gynecol Scand 2007;86:978-85. Stuard, S., Belcaro, G., Cesarone, M. R., Ricci, A., Dugall, M., Cornelli, U., Gizzi, G., Pellegrini, L., and Rohdewald, P. J. Kidney function in metabolic syndrome may be improved with Pycnogenol(R). Clin Appl.Thromb.Hemost. The active ingredients in pycnogenol can also be extracted from other sources, including peanut skin, grape seed, and witch hazel bark. J Asthma 2004;41:825-32. Sime, S. and Reeve, V. E. Protection from inflammation, immunosuppression and carcinogenesis induced by UV radiation in mice by topical Pycnogenol. J Dermatolog.Treat. View abstract. Zhang, D., Tao, Y., Gao, J., Zhang, C., Wan, S., Chen, Y., Huang, X., Sun, X., Duan, S., Schonlau, F., Rohdewald, P., and Zhao, B. Pycnogenol in cigarette filters scavenges free radicals and reduces mutagenicity and toxicity of tobacco smoke in vivo. Headache 2006;46(5):788-793. View abstract. Biol Pharm Bull 2000;23:735-7. Pycnogenol in venous disorders: a review. View abstract. View abstract. Pycnogenol can cause dizziness, gut problems, headache, and mouth ulcers.. Special Precautions & Warnings: Pregnancy and breast-feeding: Early research suggests that pycnogenol … View abstract. For example, a 156 pound goat, unstressed and healthy, produces on average about 13,000 mg of vitamin C a day. Resveratrol - 140. View abstract. Unfortunately, most of them are just okay at best. View abstract. Activity of monomeric, dimeric, and trimeric flavonoids on NO production, TNF-alpha secretion, and NF-KB-dependent gene expression in RAW 264.7 macrophages. Free radical damage from toxins plays such a fundamental role in the development of cancer, it is no wonder some of the first supplements people think of taking for fighting cancer are free radical scavenging vitamins. There would be a vastly decreased chance of stroke or heart attack. Redox.Rep. Phytother Res 2004;18(12):1027-1028. Oral administration of French maritime pine bark extract (Flavangenol((R))) improves clinical symptoms in photoaged facial skin. 2004;10(4):373-377. Cell Mol Life Sci 1998;54:1168-72. View abstract. Cells would be detoxified. View abstract. The effect of pycnogenol on the microcirculation, platelet function and ischemic myocardium in patients with coronary artery diseases. J Reprod.Med. Am J Chin Med 2001;29(3-4):469-475. Belcaro, G., Cesarone, M. R., Rohdewald, P., Ricci, A., Ippolito, E., Dugall, M., Griffin, M., Ruffini, I., Acerbi, G., Vinciguerra, M. G., Bavera, P., Di Renzo, A., Errichi, B. M., and Cerritelli, F. Prevention of venous thrombosis and thrombophlebitis in long-haul flights with pycnogenol. View abstract. Pycnogenol seems to increase the immune system. As reported in PubMed, the conclusion of one study on OPC's and colorectal cancer is: "These data indicate that OPC caused cell death by apoptosis through caspase pathways on human colorectal cancer cell line, SNU-C4.". View abstract. Are there any interactions with medications? Chovanova, Z., Muchova, J., Sivonova, M., Dvorakova, M., Zitnanova, I., Waczulikova, I., Trebaticka, J., Skodacek, I., and Durackova, Z. View abstract. These are two frequency enhanced elixirs that in powerful and altogether unique ways cause free radical damage to cancer cells. Asset, G., Bauge, E., Wolff, R. L., Fruchart, J. C., and Dallongeville, J. Pycnogenol in the management of asthma. These scores are high enough to knock out some cancers. Vinciguerra G, Belcaro G, Cesarone MR, et al. B., III. Nutrition 2000;16:330-8. Tixier JM, et al. Kimbrough, C., Chun, M., dela, Roca G., and Lau, B. H. PYCNOGENOL chewing gum minimizes gingival bleeding and plaque formation. Prospective study on 320 patients]. View abstract. Liu F, Lau BHS, Peng Q, Shah V. Pycnogenol protects vascular endothelial cells from beta-amyloid-induced injury. Cesarone, M. R., Belcaro, G., Rohdewald, P., Pellegrini, L., Ippolito, E., Scoccianti, M., Ricci, A., Dugall, M., Cacchio, M., Ruffini, I., Fano, F., Acerbi, G., Vinciguerra, M. G., Bavera, P., Di Renzo, A., Errichi, B. M., and Mucci, F. Prevention of edema in long flights with Pycnogenol. View abstract. Kohama T, Inoue M. Pycnogenol alleviates pain associated with pregnancy. Pycnogenol can cause dizziness, gut problems, headache, and mouth ulcers. View abstract. 2010;106(7):1030-1033. Researchers say that the ability to produce vitamin C gives those mammals that naturally produce it a powerful healing tool that enables them to live much longer than they would otherwise. View abstract. Schweizerische Zeitschrift fur GanzheitsMedizin 1995;3:114-115. Super high doses where you take as much as bowel tolerance allows come in a bit better at 64. 3-21-2000;2(2):73-77. Decades ago a researcher, Dr. Riordan, discovered that most cancer patients are deficient in vitamin C, especially those in advanced stages of cancer. Liu X, Zhou HJ, Rohdewald P. French maritime pine bark extract pycnogenol dose-dependently lowers glucose in type 2 diabetic patients (letter). Effects of antioxidant treatment on normal and diabetic rat retinal enzyme activities. Methods Enzymol. When talking about using antioxidants for cancer, here are a few things you should know.One of the causes of cancer is excessive free radical damage in your cells that harms your DNA and results in some cells mutating into cancerous cells.. Antioxidants get rid of free radicals. View abstract. Hosseini S, Lee J, Sepulveda RT, et al. Turns out cancer cells, because they get most of their energy from glucose, may mistake vitamin C for glucose because vitamin C is made from glucose so their structure is similar. Kobayashi, M. S., Han, D., and Packer, L. Antioxidants and herbal extracts protect HT-4 neuronal cells against glutamate-induced cytotoxicity. We have noticed that the frequency enhanced elixirs covered in this report do a very good job of telling the body to make specific enzymes. Perera, N., Liolitsa, D., Iype, S., Croxford, A., Yassin, M., Lang, P., Ukaegbu, O., and van, Issum C. Phlebotonics for haemorrhoids. Here's why a stage 4 breast cancer diagnosis can be so frightening. Disclaimer: These statements have not been evaluated by the Food and Drug Administration. Free Radic Biol Med 2001;30:154-60. For breast cancer, direct injection of ozone into the tumor is possible. Phytother Res 2000;14:472-3. At the very least, these damaged fibroblasts would be producing more lactic acid so that the micro-environment around cancer cells is more favorable to the development of cancer. What is even more impressive is that when a 156 pound goat is sick or stressed, it can produce up to 13 times more vitamin C, approximately 170,000 mg per day. This blog offers simple, actionable advice, provided to help readers on their path to optimal health, according to the principles of Andrew Weil, M.D. The proposed mechanism is related to nitric oxide preservation, as seen with grape seed extract, pycnogenol, and resveratrol. PrugX significantly and greatly increases the effectiveness of this process by inhibiting the cancer cells ability to pump out or get rid of the hydrogen peroxide that build up in them. Maritim, A., Dene, B. View abstract. Rucklidge, J. J., Johnstone, J., and Kaplan, B. J. Nutrient supplementation approaches in the treatment of ADHD. Stay on the safe side and avoid use. View abstract. View abstract. Panminerva Med 2010;52(2 Suppl 1):21-25. Good, but not near as good as many of the supplements covered in this report. View abstract. View abstract. Foster S, Tyler VE. Alpha Lipoic Acid - 160. Belcaro, G., Cesarone, M. R., Errichi, B. M., Ledda, A., Di, Renzo A., Stuard, S., Dugall, M., Pellegrini, L., Gizzi, G., Rohdewald, P., Ippolito, E., Ricci, A., Cacchio, M., Cipollone, G., Ruffini, I., Fano, F., and Hosoi, M. Diabetic ulcers: microcirculatory improvement and faster healing with pycnogenol. View abstract. View abstract. The effect of pycnogenol on the microcirculation, platelet function and ischemic myocardium in patients with coronary artery diseases. The effect of polyphenolic extract from pine bark, Pycnogenol on the level of glutathione in children suffering from attention deficit hyperactivity disorder (ADHD). Golanski, J., Muchova, J., Golanski, R., Durackova, Z., Markuszewski, L., and Watala, C. Does pycnogenol intensify the efficacy of acetylsalicylic acid in the inhibition of platelet function? View abstract. Osteoarthritis.Cartilage. Use about 12 capsules daily for an early stage cancer, 18 a day for an advanced stage cancer. Control of edema in hypertensive subjects treated with calcium antagonist (nifedipine) or angiotensin-converting enzyme inhibitors with pycnogenol. Enseleit, F., Sudano, I., Periat, D., Winnik, S., Wolfrum, M., Flammer, A. J., Frohlich, G. M., Kaiser, P., Hirt, A., Haile, S. R., Krasniqi, N., Matter, C. M., Uhlenhut, K., Hogger, P., Neidhart, M., Luscher, T. F., Ruschitzka, F., and Noll, G. Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease: a double-blind, randomized, placebo-controlled, cross-over study. Pycnogenol might slow blood clotting. Phytother.Res. See more conditions. 2011;53(3 Suppl 1):57-64. The products and information contained herein are not intended to diagnose, treat, cure, or prevent any diseases or, medical problems. J Reprod Med 2004;49:828-32. Humans, along with some other primates, bats and guinea pigs, are not able to produce vitamin C, as other mammals do. Brain tumor, breast cancer, colon cancer, congenital heart disease, heart arrhythmia. View abstract. Planta Med 1998;64:324-7. Huynh, H. T. and Teel, R. W. Selective induction of apoptosis in human mammary cancer cells (MCF-7) by pycnogenol. Buz'Zard, A. R., Peng, Q., and Lau, B. H. Kyolic and Pycnogenol increase human growth hormone secretion in genetically-engineered keratinocytes.